Children's Center investigator Juliette Madan was quoted in Nature regarding bacterial colonization of infants in utero: "There's very little in and on the human body that could be considered sterile," says Juliette Madan, a neonatologist at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire. But a handful of microbes does not necessarily mean there's a complex, thriving microbiome. Madan doesn't expect researchers to find any meaningful sharing of bacteria between mother and fetus."
Nature
Center Director Margaret Karagas was quoted in a New York Times article about exposure to arsenic through rice in infant food products.
New York Times
The NIEHS/EPA network of Children's Environmental Health and Disease Prevention Research Centers have released an impact report. See our work highlighted on pages 23, 42-43, 60, 63, 66, and 75!
Impact Report
The Dartmouth Children's Center's collaborative research with Dr. Rebecca Fry's lab on arsenic metabolites in infants and pregnant women was cited in a feature in NIEHS's Environmental Factor.
Environmental Factor
The Dartmouth Toxic Metals Superfund Research Program has launched a new site providing information on common sources of arsenic exposure.
Arsenic and You: Information on Arsenic in Food, Water & Other Sources
Dr. Diane Gilbert-Diamond was lead author on the paper, "Relation between in utero arsenic exposure and birth outcomes in a cohort of mothers and their newborns from New Hampshire," published in Environmental Health Perspectives.
Link to NIEHS announcement
Created in partnership with Dartmouth's DALI lab, we are excited to share our new tool for educating parents and the public about sources of arsenic and reducing exposure.
Click to experience the DALI tool
The Children's Environmental Health and Disease Prevention Research Center at Dartmouth invites applications for an interdisciplinary postdoctoral training and career development program in the fields of epidemiology, biostatistics and bioinformatics.
Postdoctoral Ad
The second annual Children's Environmental Health Day is on October 12, 2017! Children in the United States are routinely exposed to significant environmental hazards: at least 4 million households include children exposed to high levels of lead, and children of color and children living in poverty are disproportionately at risk. You can also visit www.cehn.org/cehday to learn more about the significance of Children's Environmental Health Day, and check out the Blueprint for Protecting Children's Environmental Health: An Urgent Call to Action (http://cehn.org/our-work/blueprint-for-protecting-childrens-health/vision-statement/) to read the recommendations and priority actions needed to intentionally protect children's health and to help frame your efforts! Here in New Hampshire, children may be exposed to contaminants such as arsenic in their private wells. The Dartmouth Children's Environmental Health and Disease Prevention Research Center is actively investigating the health impact of environmental exposures on children. Learn about our work and check out resources below.
http://www.dartmouth.edu/~childrenshealth/arsenic/
Dr. Farzan et al.'s paper in Environmental Health on maternal glucose intolerance and arsenic exposure was named a Children's Environmental Health Network article of the month for April 2017
CEHN
Dr. Margaret Karagas weighed in on a Health.com article on cooking methods to reduce arsenic in rice.
Health.com
The Center investigators' article was on infant arsenic exposure due to rice products targeted towards children.
JAMA Pediatrics
New Center Investigator Dr. Megan Romano was quoted in an Environmental Health Perspectives article on her research on breastfeeding and maternal chemical exposures.
Environmental Health Perspectives
In a study published in the International Journal of Obesity, Dr. Gilbert-Diamond found an association between FTO rs9939609 genotype and eating in the absence of hunger in response to television food advertisements.
Huffington Post articleOctober 13th is the first Children's Environmental Health Day! Together we can achieve a society where all children have access to clean air and water, safe and healthy foods, and safe toys and products.
Check out the Blueprint for protecting children's environmental health here.
Center Director Dr. Margaret Karagas discusses environmental, lifestyle, and genetic factors contributing to cancer incidence in New Hampshire on a recent episode of NHPR's The Exchange.
NHPR
In a recent study published in JAMA Pediatrics, Children’s Center researchers found that infants who ate rice and rice products had higher urinary arsenic concentrations than those who did not consume any type of rice
JAMA Pediatrics Manuscript
Children's Center Director, Dr. Margaret Karagas responds to the Food and Drug Administration's new proposed limit for inorganic arsenic in infant rice cereal
New York Times StoryChildren's Center Researchers delve into the relationship between in utero arsenic exposure and birth outcomes in a recent Environmental Health Perspectives manuscript
Link to Manuscript
Center Director, Dr. Margaret Karagas was quoted in the February 2016 Environmental Health Perspective News Science Selection "Arsenic and Latent Disease Risk: What's the Mechanism of Action?"
Link to Commentary
Children's Center co-investigator, Dr. Amar Das shares details about the exciting research and tools of Biomedical Informatics at Dartmouth.
Dartmouth Now
Children's Center Researchers report on the association of cesarean delivery and formula supplementation with the intestinal microbiome of infants in JAMA Pediatrics, which was highlighted in National Public Radio's "Science Friday," and was featured in the February NIEHS "Environmental Factor" Newsletter following the recent NAS Microbiome Workshop
Link to Manuscript
Children's Center Researchers investigate placental metal concentrations in relation to maternal and infant toenails in Environmental Science & Technology
Link to Manuscript
Recent findings published in the journal of Environmental Health Perspectives highlight work on the epigenome-wide assessment of DNA methylation in the placenta and arsenic exposure
Link to Manuscript
Dr. Carolyn Murray the Director of the Children's Center Community Outreach and Translation Core encourages everyone to test their well water for arsenic in a DHMC Imagine Better story.
DHMC Imagine Better
In a recent study led by Children's Center Investigators available in the December 2015 issue of Pediatrics, researchers explore how television food advertising may undermine the ability of parents to identify and encourage healthy choices for their children
AAP Press Release
Children's Center Researcher Dr. Diane Gilbert-Diamond was recently interviewed by New Hampshire Public Radio on the continued issues of obesity in the United States
NHPR Story
Children's Center Researchers published a study in the journal of Environmental Health Perspectives on study findings that indicate children born to women who were exposed to arsenic during pregnancy have an increased risk of infections and respiratory symptoms within in their first year of life
Link to Manuscript
In the latest release from Dartmouth-Hitchcock's Norris Cotton Cancer Center, Dr. Carolyn Murray discusses the importance of testing well water to reduce future arsenic exposure.
Link to the article
A new study from Center members discusses how maternal arsenic exposure during pregnancy can lead to respiratory infections in the infant during the first year of life.
Link to the publication
In the first and largest studies that examine variations of genetic expression and control, Center investigator Dr. Carmen Marsit and colleagues report on imprinted genes expressed in the placenta.
Link to companion paper #1Center Director, Dr. Margaret Karagas, in a collaborative commentary to further empower health care providers about the exposures of arsenic through the consumption of rice.
Click here to preview the article
In a recent Nature story, Center Director Dr. Margaret Karagas, comments on new cooking methods that flush up to 57 percent of arsenic out of rice
Link to Nature Story
The Office of the Provost announces a new collaborative cluster initiative to enhance and extend Dartmouth's successful and distinctive history in pioneering interdisciplinary programs focused on water issues. Dr. Margaret Karagas, Children's Center Director, is one of the coordinating faculty for this novel and exciting new opportunity.
Click here for full announcement
Risk of death from cardiovascular disease associated with low-level arsenic exposure among long-term smokers in a US population-based study was recently published by Center Members in Toxicology and Applied Pharmacology.
Link to article in PubMed
COTC Director, Dr. Carolyn Murray published a recent Op-Ed piece in the Valley News on the importance of testing well water for arsenic.
Valley News
Center Members are working with Congresswoman Rosa DeLauro to Introduce Legislation to Limit Inorganic Arsenic in Rice.
More on the RICE Act
A recent study published in the Journal of Pediatrics explores the dangerous relationship between energy drink consumption and the risk of alcohol use disorder amongst young adults.
Link to full story
The Children's Environmental Health and Disease Prevention Research Center was a proud co-sponsor of the 8th Annual Integrative Biology Symposium on Epigenetics, held April 21-22, 2015. This event was free and open to the public.
For More Information
Children's Center researchers investigate placental arsenic concentrations in relation to both maternal and infant biomarkers of exposure in a new study published in the Journal of Exposure Science and Environmental Epidemiology.
Link to Pub Med
Center Investigators delve into the associations between gut microbial colonization in early life and respiratory outcomes in cystic fibrosis in a recent Journal of Pediatrics manuscript.
Link to Pub Med
In a recent manuscript published in Environmental Health, Center members investigate In utero low-level arsenic exposure and fetal growth using biometric measurements extracted from fetal ultrasound reports.
Link to Pub Med
Center researchers, Drs. Emond and Gilbert-Diamond, speak to the correlation between excessive weight gain during youth and cancer risks later in life.
Link to the full story
Children's Center Researchers publish on the estimated exposure to arsenic in breastfed and formula-fed babies in Environmental Health Perspectives.
Dartmouth Now
Children's Center Researchers publish findings on the association between maternal urinary arsenic species and infant cord blood leptin levels in Environmental Research.
PubMed LinkChildren's Center Researcher Dr. Carmen Marsit Co-Directs a new $2.5 million Burroughs Wellcome Fund Grant to promote cross-discipline communications and graduate education.
Press Release
"With the Children's Environmental Health Centers, we're working to educate the community about what the science is telling us, and how it may help the community and help shape public health policy," Nadeau said.
NIEHS Newsletter Link
Dr. Margaret Karagas met with Kerri-Ann Jones, United States Assistant Secretary of State for Oceans and International Environmental and Scientific Affairs, January 2015
Drs. Margaret Karagas and Carolyn Murray met with representatives of Congresswoman Rosa Delauro regarding proposed legislation regulating arsenic content in rice, December 2014
Drs. Margaret Karagas and Carolyn Murray presented to the FDA Food Advisory Board on Arsenic Levels in Food, December 2014
FDA Committee Information
The Dartmouth Board of Trustees approved the new academic Department of Epidemiology at the Geisel School of Medicine at Dartmouth. Children's Center Director, Dr. Margaret Karagas, will lead this new department.
Dartmouth Now Release
Center Postdoctoral Fellow, Dr. Shohreh Farzan, and Center Director, Dr. Margaret Karagas attended the 2014 SRP meeting in San Jose, CA, November 12-14. Dr. Farzan presented on her KC Donnelly Award Research.
SRP Annual MeetingMembers of the Children's Center contributed to the "Health Effects and Mitigation of Arsenic: Current Research Efforts and Future Directions" Workshop and Webinar Discussion Series report, which is now available online.
Link to Report
Researchers from the Children's Center team with the Superfund Research Program, the Thayer School of Engineering at Dartmouth, and the New Hampshire Department of Health and Human Services to report on the health impacts of drinking water from private wells in New Hampshire.
Link to Report
The Children's Center proudly co-sponsored the Fifth Annual C. Everett Koop Lecture on "Corporate Threats to Children's Health - A Panel Discussion." Monday, October 6, 2014, 4:30 PM, Rockefeller Center, Silsby 028. Professors Joel Bakan, Bruce Lanphear and James Sargent presented.
Children's Center Researchers explore the Dietary-Wide Association Study (DWAS) of environmental Metal Exposure in US Children and Adults in PLoS One.
Link to PubMed
Children's Center Researchers publish findings on the association between in utero arsenic exposure and fetal immunity in Clinical Immunology
Link to PubMed
Children's Center Researchers, Drs. Carmen Marsit and Alison Paquette recently published in the Journal of Cellular Biochemistry about the serotonin receptor 5-HT2A (encoded by HTR2A), an important regulator of fetal brain development and adult cognitive function. Environmental signals that induce epigenetic changes of serotonin response genes, including HTR2A, have been implicated in adverse mental health outcomes.
Link to PubMed
In a recent manuscript published in Medical Epigenetics, Children's Center Researchers, Drs. Carmen Marsit, Corina Lesseur and Alison Paquette describe their recent body of work demonstrating that during fetal development and early-infancy environmental signals can induce epigenetic changes that alter neurobehavioral development and later-life mental health.
Link to PubMed
Children's Center Associate Director, Dr. Carol Folt, presented as a part of the 2014 NIEHS Spirit Lecture.
"We could hardly ask for a better speaker for this event," said NIEHS and NTP Director, Dr. Linda Birnbaum.
In a recent publication in the Journal of Exposure Science & Environmental Epidemiology, Children's Center Researchers from all three projects, collaboratively explore the relationship between infant toenails and in utero arsenic exposure.
Link to Journal
Dr. Karagas and colleague's recently published paper in Pediatrics on the incidence of early-onset skin cancer and associated risks with indoor tanning was cited in the newly released 2014 Surgeon General's Call to Action to Prevent Skin Cancer. The report outlines the risks and action steps to reverse the alarming rise in the incidence of skin cancers in the US population.
Manuscript Link
Children's Center Director, Dr. Margaret Karagas, was appointed to the Squires Professorship at the Geisel School of Medicine at Dartmouth.
Click to read full press release
Children's Center Researchers present in the NIEHS/EPA Children's Center Webinar Series
Dr. Kathy Cottingham will present "Hot Topics in Food Safety and Children's Health"
June 11, 2014
Dr. Carmen Marsit presented "Early Life and Epigenetics/Response and Impact on Immune System"
April 9, 2014
Children's Center Researchers, Drs. Carmen Marsit and Corina Lesseur investigate the sex-specific associations between placental leptin (a central hormone for energy honeostasis) and infant neurobehaivor, in a recent manuscript published in Psychoneuroendrocrinology.
Link to manuscript
Dr. Kathleen Bush, Research Assistant Professor, Center for the Environment at Plymouth State University, and former US EPA fellow, will visit Dartmouth and present on Thursday, May 22, 2014
Dr. Bush's Website
Several Children's Center Researchers, presented their Children's Center research at this years Pediatric Academic Societies meeting in Vancouver Canada.
Dr. Juliette Madan (Project 1): "Neonatal Microbiome, Exposures and Infection" (poster)
Dr. Shohreh Farzan (Project 1): "In Utero Arsenic Exposure and Infant Infections in the First Year of Life: A Longitudinal Study in US Cohort" (poster)
Dr. Anne Hoen (Project 1): "The Developing Gut and Respiratory Microbiome in Young Children 0-3 with CF: Clinical Correlates" (poster)
Dr. Diane Gilbert-Diamond (Project 2): "Television in the Bedroom Is Associated With Increased Adiposity Gain in a Nationally Representative Sample of Adolescents" (invited talk)
Dr. Corina Lesseur (Project 3): "Maternal Obesity and Gestational Diabetes Are Associated with Leptin DNA Methylation in Human Placenta" (poster)
Graduate Student, Alison Paquette (Project 3): "KFBP5 Placental Methylation is Associated with Infant Neurobehavioral Outcomes" (invited talk)
During an upcoming NIEHS Superfund Research Program (SRP) webinar series on the current state of knowledge and data gaps in the field of arsenic environmental health research, Dr. Marsit will serve as an expert panelist at the "Susceptibility to Arsenic Effects" webinar, May 7, 2014, 1:30-3:00 pm.
To Register for WebinarChildren's Center Director, Dr. Margaret Karagas, contributes to the Environmental Health Perspectives featured news article on "Low-Dose Arsenic: In Search of a Risk Threshold"
Link to article
Dartmouth has commissioned artist Fay Wang to compose a symphony exploring the relationship between science and music. Center Researchers were interviewed about their work, and the relationship between microbes and human health. This truly translational project is inspired by the work being done within the Children's Environmental Health and Disease Prevention Research Center at Dartmouth.
Event Details
Children's Center Researchers, Drs. Carol Folt and Carmen Marsit presented during the March NIEHS Workshop, "Health Effects and Mitigation of Arsenic: Current Research Efforts and Future Directions." The workshop highlighted significant new and emerging research on low dose exposure to arsenic in human health.
Workshop Information
Children's Center Researcher, Dr. Gilbert-Diamond, recently published a study in JAMA Pediatrics associating television in the bedroom with increased weight gain in children and adolescents.
JAMA PediatricsThe study is published in the February edition of the Journal of Medical Internet Research.
JMIR
Children's Center Postdoctoral Fellow, Dr. Shohreh Farzan, received the KC Donnelly Externship Award at the 2013 National Institute for Environmental Health Sciences Superfund Research Program Annual Meeting
Announcement
Continued coverage of a Dartmouth-led study that found diet alone can be a significant source of arsenic exposure. Of the foods tested in the study, Dartmouth researchers found that white wine, beer, dark-meat fish, and Brussels sprouts raised people's arsenic levels the most significantly. Lead researcher Kathryn Cottingham, professor of biological sciences, is quoted in the article.
http://www.livescience.com/41504-wine-and-beer-arsenic.html
Center Director Dr. Margaret Karagas serves on National Research Council committee to recommend data-driven approach for assessing multiple health effects of inorganic arsenic. Read More...
Read the Report...
Center Director, Dr. Margaret Karagas interviewed by Reuters.
Read More..
Dr. Juliette Madan interviewed for New York Times article by Carl Zimmer about the fetal and neonatal microbiome.
Read the New York Times Article
Dr. Karagas, congratulates Dr. Folt, as she take office as Carolina's 11th chancellor and first woman leader on July 1, 2013.
Read more at http://chancellor.unc.edu/
"The Allergy Buster: Can a Radical New Treatment Save Children With Severe Food Allergies?"
Read More..